| Overview |
| bs-7464R-Cy3 |
| Smad2 (Ser250) Polyclonal Antibody, Cy3 Conjugated |
| WB, FCM |
| Human, Mouse |
| Rat, Dog, Cow, Pig |
| Specifications |
| Cy3 |
| Rabbit |
| KLH conjugated synthesised phosphopeptide derived from human Smad2 around the phosphorylation site of Ser250 |
| Ser250 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 4087 |
| Q15796 |
| Cytoplasm, Nucleus |
| Smad2 (phospho S250); p-Smad2 (phospho S250); hMAD 2; hMAD 3; hSMAD2; hSMAD3; Mad related protein 2; MADH2; MADH3; MADR2; Mothers against DPP homolog 2; Mothers against DPP homolog 3; Sma and Mad related protein 2; SMA and MAD related protein 3; SMAD 2; SMAD 3; SMAD family member 2; SMAD family member 3. |
| Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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