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5-Geranyloxy-7-methoxycoumarin

Overview
Catalog # bs-76371c-1mg
Product Name 5-Geranyloxy-7-methoxycoumarin
Specifications
Storage Buffer Powder
Storage Condition Stable for 2 years after receipt when stored at -20°C.
Target
Product Information CAS Number: 7380-39-4

Molecular formula: C20H24O4

Molecular weight: 328.4

Purity: >98% (HPLC)

Appearance: White to off-white powder.

Solubility: Soluble in DMSO or chloroform.

InChiKey: WXUOSNJWDJOHGW-XNTDXEJSSA-N

SMILES: O=C1OC2=CC(OC)=CC(OC/C=C(CC/C=C(C)\C)\C)=C2C=C1

SMILES: COC1=CC(OC\C=C(/C)CCC=C(C)C)=C2C=CC(=O)OC2=C1
Description 5-Geranyloxy-7-methoxycoumarin is a natural coumarin found in the essential oils of citrus such as bergamot, which shows antifungal, antibacterial, and anticancer activity. 5-Geranyloxy-7-methoxycoumarin arrests cells at the G0/G1 phase and induces apoptosis through activation of tumour suppressor gene p53, caspase8/3, regulation of Bcl2 and inhibition of p38 MAPK phosphorylation.