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5-Hydroxydiclofenac

Overview
Catalog # bs-76390c-5mg
Product Name 5-Hydroxydiclofenac
Specifications
Storage Buffer Powder
Storage Condition Stable for 2 years after receipt when stored at -20°C.
Target
Product Information CAS Number: 69002-84-2

Molecular formula: C14H11Cl2NO3

Molecular weight: 312.2

Purity: >97% (HPLC)

Appearance: Light grey powder.

Solubility: Soluble in DMSO or acetone.

InChiKey: VNQURRWYKFZKJZ-UHFFFAOYSA-N

SMILES: OC1=CC=C(NC2=C(Cl)C=CC=C2Cl)C(CC(O)=O)=C1

SMILES: OC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC(O)=C1
Description Metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound that functions via inhibiton of cyclooxygenase (COX). Diclofenac undergoes biotransformation not only by glucuronidation, but also by cytochrome P450–mediated oxidation to produce 4'-OH-DFN and 5-OH-DFN, which undergo subsequent oxidation to form highly electrophilic benzoquinone imine intermediates. Compound can be used as analytical reference material.