5-Hydroxydiclofenac
| Overview | |
| Catalog # | bs-76390c-5mg |
| Product Name | 5-Hydroxydiclofenac |
| Specifications | |
| Storage Buffer | Powder |
| Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 69002-84-2 Molecular formula: C14H11Cl2NO3 Molecular weight: 312.2 Purity: >97% (HPLC) Appearance: Light grey powder. Solubility: Soluble in DMSO or acetone. InChiKey: VNQURRWYKFZKJZ-UHFFFAOYSA-N SMILES: OC1=CC=C(NC2=C(Cl)C=CC=C2Cl)C(CC(O)=O)=C1 SMILES: OC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC(O)=C1 |
| Description | Metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound that functions via inhibiton of cyclooxygenase (COX). Diclofenac undergoes biotransformation not only by glucuronidation, but also by cytochrome P450–mediated oxidation to produce 4'-OH-DFN and 5-OH-DFN, which undergo subsequent oxidation to form highly electrophilic benzoquinone imine intermediates. Compound can be used as analytical reference material. |