4-Methylumbelliferyl phosphate disodium salt

Overview
Catalog #	bs-76498c-250mg
Product Name	4-Methylumbelliferyl phosphate disodium salt
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 22919-26-2 Molecular formula: C10H7Na2O6P Molecular weight: 300.11 Purity: >97% (NMR) Appearance: White to off-white powder. Solubility: Soluble in water (50 mg/ml). InChiKey: WUUDJQVNZPEPKN-UHFFFAOYSA-L SMILES: CC(C1=CC=C(OP([O-])([O-])=O)C=C1O2)=CC2=O.[Na+].[Na+] SMILES: [Na+].[Na+].CC1=CC(=O)OC2=CC(OP([O-])([O-])=O)=CC=C12
Description	4-Methylumbelliferyl phosphate (4-MUP) is a fluorogenic substrate for phosphatases (mainly alkaline). It is converted to the fluorescent product 4-methylumbelliferone (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. Therefore, this phosphatase substrate is not well suited for living cell or continuous assays since 4-MU only develops maximum fluorescence at a pH value of >10. Spectral data: lambdaex=319nm; lambdaem=384nm (pH 9.0). lambdaex=360nm; lambdaem=449nm (for reaction product).