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Bimatoprost

Overview
Catalog # bs-76718c-1mg
Product Name Bimatoprost
Specifications
Storage Buffer Powder
Storage Condition Stable for 2 years after receipt when stored at -20°C.
Target
Product Information CAS Number: 155206-00-1

Molecular formula: C25H37NO4

Molecular weight: 415.57

Purity: >95% (HPLC)

Appearance: White powder.

Solubility: Soluble in DMSO.

InChiKey: AQOKCDNYWBIDND-FTOWTWDKSA-N

SMILES: O[C@H]1C[C@@H](O)[C@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H]1C/C=C\CCCC(NCC)=O

SMILES: CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC1=CC=CC=C1
Description Bimatoprost is a synthetic prostamide FP receptor agonist, structurally related to prostaglandin F2alpha that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. Bimatoprost is therefore an antiglaucoma agent. Bimatoprost is converted by an amidase enzymatic activity to yield the corresponding free acid, 17-phenyl trinor PGF2alpha, a potent PGF2alphaR agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity.