6-Mercaptopurine

Overview
Catalog #	bs-82995c-200-mg
Product Name	6-Mercaptopurine
Specifications
Storage Buffer	Yellow solid
Storage Condition	RT
Target
Product Information	Purine antimetabolite drug used to treat acute lymphocytic leukemia, Crohn’s disease, ulcerative colitis, and inflammatory bowel disease.1 It inhibits DNA synthesis by inhibiting the production of purine containing nucleotides. The immunomodulatory activity of 6-Mercaptopurine is mainly the result of the 6-MP metabolite 6-thioguanine triphosphate (6-TGTP) binding to small GTPase Rac1.2
Description	CAS Number: 6112-76-1 Chemical Name: 3,7-Dihydropurine-6-thione monohydrate Molecular weight: 170.19 Formula: C5H4N4S·H2O Solubility: DMSO (>50 mg/ml) Ethanol (5 mg/ml with warming) Physical Properties: Yellow solid Purity: >98% by HPLC NMR (Conforms)