Asunaprevir

Overview
Catalog #	bs-83420c-25mg
Product Name	Asunaprevir
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Asunaprevir is a potent hepatitis C virus NS3 protease inhibitor (IC50 = 0.2 – 3.5 nM).1 Asunaprevir was used as part of a repressible Cas9 system (small molecule-assisted shut off – SMASh) capable of degrading newly synthesized Cas9 protein rapidly to precisely control gene editing.2,3 The Asunapreivr/SMASh system has also been using to target endogenous PD-1 protein for proteasomal degradation.4
Description	CAS Number: 630420-16-5 Chemical Name: HCV NS3 protease inhibitor/CRISPR enhancer Molecular Weight: 748.29 Formula: C35H46ClN5O9S Solubility: DMSO (>50 mg/ml) Physical Properties: White solid Purity: >98% by HPLC NMR (Conforms)