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AT7519 HCl

Overview
Catalog # bs-83812c-5mg
Product Name AT7519 HCl
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information AT7519 is a potent CDK inhibitor. Inhibits CDKs 1,2,4,5,6, and 9 (IC50s respectively: 210 nM, 47 nM, 100 nM, 13 nM, 170 nM, and <10 nM).1,2 Active in multiple human cancer cell lines.3-7 AT7519 has also been found to be a human RORγt agonist.8
Description CAS Number: 902135-91-5

Chemical Name: 4-[(2,6-Dichlorobenzoyl)amino]-N-piperidin-4-yl-1H-pyrazole-5-carboxamide hydrochloride

Molecular Weight: 418.7

Formula: C16H17Cl2N5O2·HCl

Solubility: DMSO (>25 mg/ml)

Physical Properties: White solid

Purity: >98% by HPLC NMR (Conforms)