ATG4C (7C2) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51084M-100uL |
| Product Name | ATG4C (7C2) Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein. |
| Clonality | Monoclonal |
| Clone # | 7C2 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purifie |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 84938 |
| Swiss Prot | Q96DT6 |
| Synonyms | APG4C; AUTL1; AUTL3; APG4-C; Cysteine protease ATG4C; AUT-like 3 cysteine endopeptidase; Autophagin-3; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C; ATG4C |
| Background | Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is ATG4C (7C2) Monoclonal Antibody (bsm-51084M) validated for, and at what dilution?
bsm-51084M is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ATG4C (7C2) Monoclonal Antibody (bsm-51084M) react with?
Tested reactivity: Mouse.
How should bsm-51084M be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ATG4C (7C2) Monoclonal Antibody (bsm-51084M)?
This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein.