FMR1 (8C2) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51162m-100uL |
| Product Name | FMR1 (8C2) Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1. |
| Clonality | Monoclonal |
| Clone # | 8C2 |
| Isotype | IgM |
| Concentration | Lot Dependent |
| Purification | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 2332 |
| Swiss Prot | Q06787 |
| Synonyms | POF; FMRP; POF1; FRAXA; Synaptic functional regulator FMR1; Fragile X mental retardation protein 1; Protein FMR-1; FMR1 |
| Background | The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is FMR1 (8C2) Monoclonal Antibody (bsm-51162M) validated for, and at what dilution?
bsm-51162M is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does FMR1 (8C2) Monoclonal Antibody (bsm-51162M) react with?
Tested reactivity: Human.
How should bsm-51162M be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise FMR1 (8C2) Monoclonal Antibody (bsm-51162M)?
This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1.