MCM3 (3C3) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51337M-100uL |
| Product Name | MCM3 (3C3) Monoclonal Antibody |
| Applications |
WB
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This MCM3 antibody is generated from a mouse immunized with a recombinant protein of human MCM3. |
| Clonality | Monoclonal |
| Clone # | 3C3 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 4172 |
| Swiss Prot | P25205 |
| Synonyms | HCC5; P1.h; RLFB; P1-MCM3; DNA replication licensing factor MCM3; DNA polymerase alpha holoenzyme-associated protein P1; RLF subunit beta; p102; MCM3 |
| Background | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation. |
| Application Dilution | |
| WB | 1:300-5000 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is MCM3 (3C3) Monoclonal Antibody (bsm-51337M) validated for, and at what dilution?
bsm-51337M is validated for WB (1:300-5000); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does MCM3 (3C3) Monoclonal Antibody (bsm-51337M) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-51337M be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise MCM3 (3C3) Monoclonal Antibody (bsm-51337M)?
This MCM3 antibody is generated from a mouse immunized with a recombinant protein of human MCM3.