BCL10 (5C2) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51398M-100uL |
| Product Name | BCL10 (5C2) Monoclonal Antibody |
| Applications |
WB
IF
IHC-P
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This BCL10 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-143 amino acids from the human region of human BCL10. |
| Clonality | Monoclonal |
| Clone # | 5C2 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purifie |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 8915 |
| Swiss Prot | O95999 |
| Synonyms | CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; Mammalian CARD-containing adapter molecule E10; BCL10 |
| Background | Involved in adaptive immune response (PubMed:25365219). Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101). |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | 1:50-200 |
| IHC-P | 1:200-400 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is BCL10 (5C2) Monoclonal Antibody (bsm-51398M) validated for, and at what dilution?
bsm-51398M is validated for WB (1:300-5000); IF (1:50-200); IHC-P (1:200-400); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does BCL10 (5C2) Monoclonal Antibody (bsm-51398M) react with?
Tested reactivity: Human.
How should bsm-51398M be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise BCL10 (5C2) Monoclonal Antibody (bsm-51398M)?
This BCL10 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-143 amino acids from the human region of human BCL10.