ALDH2 (8C8) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51417M-100uL |
| Product Name | ALDH2 (8C8) Monoclonal Antibody |
| Applications |
WB
IF
IHC-P
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This ALDH2 Monoclonal antibody is generated from mouse immunized with ALDH2 recombinant protein. |
| Clonality | Monoclonal |
| Clone # | 8C8 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purifie |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 217 |
| Swiss Prot | P05091 |
| Synonyms | ALDM; ALDHI; ALDH-E2; Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH2 |
| Background | This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | 1:50-200 |
| IHC-P | 1:200-400 |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is ALDH2 (8C8) Monoclonal Antibody (bsm-51417M) validated for, and at what dilution?
bsm-51417M is validated for WB (1:300-5000); IF (1:50-200); IHC-P (1:200-400); FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ALDH2 (8C8) Monoclonal Antibody (bsm-51417M) react with?
Tested reactivity: Human.
How should bsm-51417M be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ALDH2 (8C8) Monoclonal Antibody (bsm-51417M)?
This ALDH2 Monoclonal antibody is generated from mouse immunized with ALDH2 recombinant protein.