TSC1 Monoclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-51504m-100uL |
| Product Name | TSC1 Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Mouse |
| Predicted Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Recombinant human TSC1 (Fragment) (His-tagged). |
| Clonality | Monoclonal |
| Clone # | K6F13 |
| Isotype | IgG2b |
| Concentration | Lot Dependent |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 7248 |
| Swiss Prot | Q92574 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | LAM; Hamartin; Tuberous sclerosis 1 protein; TSC1_HUMAN; KIAA0243; TSC; Tuberous sclerosis 1. |
| Background | In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. |
| Application Dilution | |
| WB | =1:500-2000 |
Frequently asked questions
Which applications is TSC1 Monoclonal Antibody (bsm-51504M) validated for, and at what dilution?
bsm-51504M is validated for WB (WB=1:500-2000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does TSC1 Monoclonal Antibody (bsm-51504M) react with?
Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Human.
How should bsm-51504M be stored?
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise TSC1 Monoclonal Antibody (bsm-51504M)?
Recombinant human TSC1 (Fragment) (His-tagged).