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Histone H2A (hydroxyl Y39) (2A3) Monoclonal Antibody

Applications

  • WB
  • IHC
  • IHC-P

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-52286R-100uL
Product Name Histone H2A (hydroxyl Y39) (2A3) Monoclonal Antibody
Applications
WB IHC IHC-P
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic peptide surrounding Y39 of Histone H2A
Modification Site hydroxyl Y39
Clonality Monoclonal
Clone # 2A3
Isotype IgG
Concentration Lot Dependent
Purification purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3012; 8335
Swiss Prot P04908
Synonyms Histone H2A.1, Histone H2A.2, Histone H2A type 1-B/E, Histone H2A type 1-C, Histone H2A type 1-J, Histone H2A/e, Histone H2A/l, H2A2, HIST1H2AB, HIST1H2AC, HIST1H2AJ; Histone H2A.2; Histone H2A/a; Histone H2A/m
Background Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Application Dilution
WB 1:300-5000
IHC 1:50-200
IHC-P 1:200-400

Frequently asked questions

Which applications is Histone H2A (hydroxyl Y39) (2A3) Monoclonal Antibody (bsm-52286R) validated for, and at what dilution?

bsm-52286R is validated for WB (1:300-5000); IHC (1:50-200); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does Histone H2A (hydroxyl Y39) (2A3) Monoclonal Antibody (bsm-52286R) react with?

Tested reactivity: Human, Mouse, Rat.

How should bsm-52286R be stored?

Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise Histone H2A (hydroxyl Y39) (2A3) Monoclonal Antibody (bsm-52286R)?

Synthetic peptide surrounding Y39 of Histone H2A

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US only. One sample per paid order, subject to review. Backorders may ship separately. Confirm Free at checkout. Check application and species suitability; same target does not guarantee equivalent performance. For research use only.

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