CD13 Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52618r-100uL |
| Product Name | CD13 Recombinant Antibody |
| Applications |
WB
IHC-F
IF(IHC-P)
IF(ICC)
IHC-P
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Human CD13 between 1 to 260 amino acids |
| Clonality | Monoclonal |
| Clone # | 20B5 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 290 |
| Swiss Prot | P15144 |
| Synonyms | Aminopeptidase N, Alanyl aminopeptidase, Aminopeptidase M, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, gp150, CD_antigen: CD13, AP-N, hAPN, AP-M, ANPEP |
| Background | Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection. |
| Application Dilution | |
| WB | 1:500-2000 |
| IHC-F | IHC-F1:100-500 |
| IF(IHC-P) | IFIHC-P1:100-500 |
| IF(ICC) | IFICC1:100-500 |
| IHC-P | IHC-P1:100-500 |
Frequently asked questions
Which applications is CD13 Recombinant Antibody (bsm-52618R) validated for, and at what dilution?
bsm-52618R is validated for WB(WB) (1:500-2000); IHC-F(IHC-F) (1:100-500); IF(IHC-P)(IF(IHC-P)) (1:100-500); IF(ICC)(IF(ICC)) (1:100-500); IHC-P(IHC-P) (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CD13 Recombinant Antibody (bsm-52618R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-52618R be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CD13 Recombinant Antibody (bsm-52618R)?
Human CD13 between 1 to 260 amino acids