DYNLL1 (9T1) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52688R-100uL |
| Product Name | DYNLL1 (9T1) Monoclonal Antibody |
| Applications |
WB
IF(ICC)
IHC
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | N terminus Human DYNLL1 |
| Clonality | Monoclonal |
| Clone # | 9T1 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 8655 |
| Swiss Prot | P63167 |
| Synonyms | Dynein light chain 1, cytoplasmic, 8 kDa dynein light chain, Dynein light chain LC8-type 1, Protein inhibitor of neuronal nitric oxide synthase, DLC8, PIN, DYNLL1 |
| Background | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Binds and inhibits the catalytic activity of neuronal nitric oxide synthase. Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(ICC) | 1:50-200 |
| IHC | 1:50-200 |
Frequently asked questions
Which applications is DYNLL1 (9T1) Monoclonal Antibody (bsm-52688R) validated for, and at what dilution?
bsm-52688R is validated for WB (1:300-5000); IF(ICC) (1:50-200); IHC (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does DYNLL1 (9T1) Monoclonal Antibody (bsm-52688R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-52688R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise DYNLL1 (9T1) Monoclonal Antibody (bsm-52688R)?
N terminus Human DYNLL1