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Phospho-NCOA3 (Thr24) Polyclonal Antibody, AbBy Fluor-488 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human

Predicted Reactivity

  • Pig
  • Horse
  • Rabbit
  • GuineaPig
Overview
Catalog # bs-3408R-BF488
Product Name Phospho-NCOA3 (Thr24) Polyclonal Antibody, AbBy Fluor-488 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Human
Predicted Reactivity Pig, Horse, Rabbit, GuineaPig
Specifications
Conjugation AbBy Fluor-488
Host Rabbit
Source KLH conjugated synthetic phosphopeptide derived from human SRC-3 around the phosphorylation site of Thr24
Modification Site Thr24
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8202
Subcellular location Cytoplasm, Cell membrane
Synonyms ACTR; AIB 1; AIB-1; AIB1; Amplied in breast cancer 1; Amplied in breast cancer 1 protein; bHLHe42; CAGH 16; CAGH16; CBP interacting protein; CBP-interacting protein; Class E basic helix-loop-helix protein 42; CTG 26; CTG26; KAT13B / AIB1; MGC141848; NCOA 3; NCOA 3; NCoA-3; Ncoa3; NCOA3_HUMAN; Nuclear receptor coactivator 3; pCIP; RAC 3; RAC-3; RAC3; Receptor associated coactivator 3; Receptor-associated coactivator 3; SRC 3; SRC-3; SRC3; Steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; TRAM 1; TRAM-1; TRAM1.
Background KAT13B/AIB1 interacts in a ligand-dependent fashion with the estrogen receptor to enhance estrogen-dependent transcriptional gene activation. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits KAT3A / KAT3B as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

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