| Overview |
| bsm-52270r-percp-cy7-100ul |
| DUSP6 Recombinant Antibody, PerCP-Cy7 Conjugated |
| WB |
| Human, Mouse, Rat |
| Specifications |
| PerCP-Cy7 |
| Rabbit |
| Recombinant protein within Human DUSP6 aa 1-350 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1848 |
| Q16828 |
| Cytoplasm |
| Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3 |
| Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity). Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
Powered by Bioz