Aph-1b Polyclonal Antibody, Cy5.5 Conjugated
Applications
Predicted Reactivity
| Overview | |
| Catalog # | bs-11640R-Cy5.5-100uL |
| Product Name | Aph-1b Polyclonal Antibody, Cy5.5 Conjugated |
| Applications |
WB
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Predicted Reactivity | Human, Mouse, Rat, Dog, Cow, Sheep, Pig |
| Specifications | |
| Conjugation | Cy5.5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Aph-1b |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 83464 |
| Swiss Prot | Q8WW43 |
| Subcellular location | Cell membrane |
| Synonyms | PSFL; APH-1B; PRO1328; TAAV688; Gamma-secretase subunit APH-1B; Aph-1beta; Presenilin-stabilization factor-like; APH1B; UNQ688/PRO1328 |
| Background | Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is Aph-1b Polyclonal Antibody, Cy5.5 Conjugated (BS-11640R-CY5-5) validated for, and at what dilution?
BS-11640R-CY5-5 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
How should BS-11640R-CY5-5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Aph-1b Polyclonal Antibody, Cy5.5 Conjugated (BS-11640R-CY5-5)?
KLH conjugated synthetic peptide derived from human Aph-1b
What are the excitation and emission wavelengths of the Cy5.5 conjugate (BS-11640R-CY5-5)?
Cy5.5 on BS-11640R-CY5-5: excitation / emission 675nm/694nm.