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Aph-1b Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Cow
  • Sheep
  • Pig
Overview
Catalog # bs-11640R-HRP-100uL
Product Name Aph-1b Polyclonal Antibody, HRP Conjugated
Applications
WB ELISA IHC-P IHC-F
Predicted Reactivity Human, Mouse, Rat, Dog, Cow, Sheep, Pig
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Aph-1b
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 83464
Swiss Prot Q8WW43
Subcellular location Cell membrane
Synonyms PSFL; APH-1B; PRO1328; TAAV688; Gamma-secretase subunit APH-1B; Aph-1beta; Presenilin-stabilization factor-like; APH1B; UNQ688/PRO1328
Background Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Frequently asked questions

Which applications is Aph-1b Polyclonal Antibody, HRP Conjugated (bs-11640R-HRP) validated for, and at what dilution?

bs-11640R-HRP is validated for WB (1:300-5000); ELISA (1:500-1000); IHC-P (1:200-400); IHC-F (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

How should bs-11640R-HRP be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise Aph-1b Polyclonal Antibody, HRP Conjugated (bs-11640R-HRP)?

KLH conjugated synthetic peptide derived from human Aph-1b

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