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SOX2 Polyclonal Antibody, PE-Cy7 Conjugated

Applications

  • WB

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Cow
  • Sheep
  • Horse
  • Chicken
Overview
Catalog # bs-23177R-PE-Cy7-100uL
Product Name SOX2 Polyclonal Antibody, PE-Cy7 Conjugated
Applications
WB
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Cow, Sheep, Horse, Chicken
Specifications
Conjugation PE-Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human SOX2
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 6657
Swiss Prot P48431
Subcellular location Cytoplasm, Nucleus
Synonyms Transcription factor SOX-2; SOX2;
Background Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is SOX2 Polyclonal Antibody, PE-Cy7 Conjugated (bs-23177R-PE-Cy7) validated for, and at what dilution?

bs-23177R-PE-Cy7 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does SOX2 Polyclonal Antibody, PE-Cy7 Conjugated (bs-23177R-PE-Cy7) react with?

Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Dog, Cow, Sheep, Horse, Chicken.

How should bs-23177R-PE-Cy7 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise SOX2 Polyclonal Antibody, PE-Cy7 Conjugated (bs-23177R-PE-Cy7)?

KLH conjugated synthetic peptide derived from human SOX2

What are the excitation and emission wavelengths of the PE-Cy7 conjugate (bs-23177R-PE-Cy7)?

PE-Cy7 on bs-23177R-PE-Cy7: excitation / emission 488nm/780nm.

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