ABCA1 Polyclonal Antibody, Cy5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-23419r-cy5-100uL |
| Product Name | ABCA1 Polyclonal Antibody, Cy5 Conjugated |
| Applications |
IF
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat |
| Specifications | |
| Conjugation | Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ABCA1 |
| Immunogen Range | 501-600/2261 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Affinity purified by Protein A |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 19 |
| Swiss Prot | O95477 |
| Subcellular location | Extracellular |
| Synonyms | ABC-1; ABC1; CERP; HDLCQTL13; TGD; ABCA1_HUMAN; ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1 (ABC-1 | ATP-binding cassette 1); cassette subfamily A member 1; ATP-binding cassette, sub-family A (ABC1), member 1; Tangier disease |
| Background | ABCA1 is a membrane-associated ATP-binding cassette transporter involved in cellular lipid homeostasis. It promotes the efflux of cholesterol and phospholipids to apolipoproteins, supporting the formation of nascent high-density lipoproteins (HDLs). ABCA1 preferentially transports phosphatidylcholine and plays an important role in cholesterol removal pathways. Mutations in ABCA1 are associated with Tangier disease and familial HDL deficiency, making it a relevant marker for lipid metabolism, cholesterol transport, cardiovascular research, and related disease studies. |
| Application Dilution | |
| IF | 1:100-500 |
Frequently asked questions
Which applications is ABCA1 Polyclonal Antibody, Cy5 Conjugated (bs-23419R-Cy5) validated for, and at what dilution?
bs-23419R-Cy5 is validated for IF (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ABCA1 Polyclonal Antibody, Cy5 Conjugated (bs-23419R-Cy5) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat.
How should bs-23419R-Cy5 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ABCA1 Polyclonal Antibody, Cy5 Conjugated (bs-23419R-Cy5)?
KLH conjugated synthetic peptide derived from human ABCA1 Immunogen range: 501-600/2261.
What are the excitation and emission wavelengths of the Cy5 conjugate (bs-23419R-Cy5)?
Cy5 on bs-23419R-Cy5: excitation / emission 625,650nm/670nm.