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TGF beta Receptor I Polyclonal Antibody, FITC Conjugated

Applications

  • WB
  • IF

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
  • Dog
  • Cow
  • Sheep
  • Pig
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-23445R-FITC-100uL
Product Name TGF beta Receptor I Polyclonal Antibody, FITC Conjugated
Applications
WB IF
Reactivity Human
Predicted Reactivity Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Specifications
Conjugation FITC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human TGF beta Receptor I
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7046
Swiss Prot P36897
Subcellular location Cell membrane
Synonyms TGFBR1; TGF Beta R1; TGF beta Receptor I; AAT 5; AAT5; Activin A receptor type II like kinase 53kDa; Activin receptor like kinase 5; ACVRLK 4; ACVRLK4; ALK 5; ALK5; Serine/threonine protein kinase receptor R4; SKR 4; SKR4; TbetaR I; TGF beta receptor type 1; TGF beta receptor type I; TGF beta type I receptor; TGFBR 1; TGFBR1 protein; TGFR 1; TGFR1; Transforming growth factor beta receptor I;TGF-??R???????; TGF??R???????; TGF-??R ???????; TGF-?? R???????.
Background On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
Application Dilution
WB 1:300-5000
IF

Frequently asked questions

Which applications is TGF beta Receptor I Polyclonal Antibody, FITC Conjugated (bs-23445R-FITC) validated for, and at what dilution?

bs-23445R-FITC is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does TGF beta Receptor I Polyclonal Antibody, FITC Conjugated (bs-23445R-FITC) react with?

Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit.

How should bs-23445R-FITC be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise TGF beta Receptor I Polyclonal Antibody, FITC Conjugated (bs-23445R-FITC)?

KLH conjugated synthetic peptide derived from human TGF beta Receptor I

What are the excitation and emission wavelengths of the FITC conjugate (bs-23445R-FITC)?

FITC on bs-23445R-FITC: excitation / emission 494nm/518nm.

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