ACVRL1 Polyclonal Antibody, Cy5.5 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-6020r-cy55-100uL |
| Product Name | ACVRL1 Polyclonal Antibody, Cy5.5 Conjugated |
| Applications |
WB
IF(IHC-P)
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Cy5.5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ALK1 |
| Immunogen Range | 30-80/503 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 94 |
| Swiss Prot | P37023 |
| Subcellular location | Extracellular |
| Synonyms | HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1; Serine/threonine-protein kinase receptor R3; Activin receptor-like kinase 1; TGF-B superfamily receptor type I; ACVRL1 |
| Background | Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
Frequently asked questions
Which applications is ACVRL1 Polyclonal Antibody, Cy5.5 Conjugated (BS-6020R-CY5-5) validated for, and at what dilution?
BS-6020R-CY5-5 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ACVRL1 Polyclonal Antibody, Cy5.5 Conjugated (BS-6020R-CY5-5) react with?
Tested reactivity: Human, Mouse, Rat.
How should BS-6020R-CY5-5 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ACVRL1 Polyclonal Antibody, Cy5.5 Conjugated (BS-6020R-CY5-5)?
KLH conjugated synthetic peptide derived from human ALK1 Immunogen range: 30-80/503.
What are the excitation and emission wavelengths of the Cy5.5 conjugate (BS-6020R-CY5-5)?
Cy5.5 on BS-6020R-CY5-5: excitation / emission 675nm/694nm.