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CMYA2 Polyclonal Antibody, APC-Cy7 Conjugated

Applications

  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-9477R-APC-Cy7-100uL
Product Name CMYA2 Polyclonal Antibody, APC-Cy7 Conjugated
Applications
IF(IHC-P)
Reactivity Human, Mouse, Rat
Specifications
Conjugation APC-Cy7
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CMYA2/PDE4DIP
Immunogen Range 1501-1600/2365
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 9659
Synonyms Cardiomyopathy associated protein 2; Cardiomyopathy-associated protein 2; CMYA2; MMGL; MYOME_HUMAN; Myomegalin; Pde4dip; Phosphodiesterase 4D interacting protein; Phosphodiesterase 4D-interacting protein.
Background May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.Myomegalin, is a 2,346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events.
Application Dilution
IF(IHC-P) 1:50-200

Frequently asked questions

Which applications is CMYA2 Polyclonal Antibody, APC-Cy7 Conjugated (bs-9477R-APC-Cy7) validated for, and at what dilution?

bs-9477R-APC-Cy7 is validated for IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does CMYA2 Polyclonal Antibody, APC-Cy7 Conjugated (bs-9477R-APC-Cy7) react with?

Tested reactivity: Human, Mouse, Rat.

How should bs-9477R-APC-Cy7 be stored?

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise CMYA2 Polyclonal Antibody, APC-Cy7 Conjugated (bs-9477R-APC-Cy7)?

KLH conjugated synthetic peptide derived from human CMYA2/PDE4DIP Immunogen range: 1501-1600/2365.

What are the excitation and emission wavelengths of the APC-Cy7 conjugate (bs-9477R-APC-Cy7)?

APC-Cy7 on bs-9477R-APC-Cy7: excitation / emission 650nm/780nm.

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US only. One sample per paid order, subject to review. Backorders may ship separately. Confirm Free at checkout. Check application and species suitability; same target does not guarantee equivalent performance. For research use only.

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