Streptokinase Polyclonal Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9846R-APC-100uL |
| Product Name | Streptokinase Polyclonal Antibody, APC Conjugated |
| Applications |
IF(IHC-P)
|
| Reactivity | Bacteria |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from Streptococcus uberis PauA protein |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 24161944 |
| Swiss Prot | B9DW72 |
| Subcellular location | Extracellular, Secreted |
| Synonyms | PauA; Plasminogen activator A; SUB1785; Streptokinase; Streptococcus uberis |
| Background | Plasminogen activator A (PauA) is a Streptococcus uberis protein that functions similarly to proteins within the Staphylokinase/Streptokinase family. Streptococcus uberis is a common cause of infection and inflammatory disease in the bovine udder. Inflammation of breast tissue (mastitis) has been recognized as a serious threat to the welfare of the dairy cow and has a severe economic impact on the dairy industry. S. uberis has been shown to specifically activate bovine and ovine plasminogen and this is mediated by the extracellular protein, plasminogen activator uberis (PauA), which has a molecular mass of around 30 kDa. It has been postulated that activation of plasminogen by PauA may facilitate early bacterial colonization of the lactating gland by promoting the release of nutrients which are likely to be restricted in milk. (https://www.ncbi.nlm.nih.gov/pubmed/10483719). |
| Application Dilution | |
| IF(IHC-P) | 1:50-200 |
Frequently asked questions
Which applications is Streptokinase Polyclonal Antibody, APC Conjugated (bs-9846R-APC) validated for, and at what dilution?
bs-9846R-APC is validated for IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Streptokinase Polyclonal Antibody, APC Conjugated (bs-9846R-APC) react with?
Tested reactivity: Bacteria.
How should bs-9846R-APC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Streptokinase Polyclonal Antibody, APC Conjugated (bs-9846R-APC)?
KLH conjugated synthetic peptide derived from Streptococcus uberis PauA protein
What are the excitation and emission wavelengths of the APC conjugate (bs-9846R-APC)?
APC on bs-9846R-APC: excitation / emission 650nm/660nm.