TIMP-1 Monoclonal Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-10895m-biotin-100uL |
| Product Name | TIMP-1 Monoclonal Antibody, Biotin Conjugated |
| Applications |
WB
IHC-F
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Mouse |
| Source | Recombinant human TIMP-1 |
| Clonality | Monoclonal |
| Clone # | 4C2 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 7076 |
| Swiss Prot | P01033 |
| Synonyms | Clgi; Collagenase inhibitor; EPA; EPO; Erythroid Potentiating Activity; Fibroblast collagenase inhibitor; FLJ90373; HC; Human Collagenase Inhibitor; Metalloproteinase inhibitor 1; Metalloproteinase inhibitor 1 precursor; OTTHUMP00000023214; TIMP 1; TIMP; TIMP metallopeptidase inhibitor 1; TIMP1 protein; Tissue Inhibitor of Metalloproteinase 1; Tissue inhibitor of metalloproteinases; Tissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor. |
| Background | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq]. |
| Application Dilution | |
| WB | 1:1000-10000 |
| IHC-F | 1:2000-10000 |
Frequently asked questions
Which applications is TIMP-1 Monoclonal Antibody, Biotin Conjugated (bsm-10895M-Biotin) validated for, and at what dilution?
bsm-10895M-Biotin is validated for WB (1:1000-10000); IHC-F (1:2000-10000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does TIMP-1 Monoclonal Antibody, Biotin Conjugated (bsm-10895M-Biotin) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-10895M-Biotin be stored?
Store at -20°C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise TIMP-1 Monoclonal Antibody, Biotin Conjugated (bsm-10895M-Biotin)?
Recombinant human TIMP-1