mouse CD16/32 Rat, AbBy Fluor-647 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-30155a-bf647-100uL |
| Product Name | mouse CD16/32 Rat, AbBy Fluor-647 Conjugated |
| Applications |
FCM
|
| Reactivity | Mouse |
| Specifications | |
| Conjugation | AbBy Fluor-647 |
| Host | Rat |
| Clonality | Monoclonal |
| Clone # | 6G10 |
| Isotype | IgG2a κ |
| Concentration | n/a |
| Purification | Purified by Protein G. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 14131 |
| Swiss Prot | P08508 |
| Synonyms | FCG3A_HUMAN; Low affinity immunoglobulin gamma Fc region receptor III-A; CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD_antigen: D16a; FCGR3A; CD16A; FCG3; FCGR3; IGFR3. |
| Background | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020] |
| Application Dilution | |
| FCM | |
Frequently asked questions
Which applications is mouse CD16/32 Rat, AbBy Fluor-647 Conjugated (bsm-30155A-BF647) validated for, and at what dilution?
bsm-30155A-BF647 is validated for FCM.
Which species does mouse CD16/32 Rat, AbBy Fluor-647 Conjugated (bsm-30155A-BF647) react with?
Tested reactivity: Mouse.
How should bsm-30155A-BF647 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What are the excitation and emission wavelengths of the AbBy Fluor-647 conjugate (bsm-30155A-BF647)?
AbBy Fluor-647 on bsm-30155A-BF647: excitation / emission 650nm/665nm.