Human S100B (7F3) Monoclonal Antibody, HRP Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-41680M-HRP-100uL |
| Product Name | Human S100B (7F3) Monoclonal Antibody, HRP Conjugated |
| Applications |
ELISA
|
| Reactivity | Human |
| Specifications | |
| Conjugation | HRP |
| Host | Mouse |
| Source | Recombinant human S100B protein |
| Clonality | Monoclonal |
| Clone # | 7F3 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 6285 |
| Swiss Prot | P04271 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | NEF; Protein S100 B; Protein S100-B; S 100 calcium binding protein beta chain; S 100 protein beta chain; S 100 protein beta subunit; S-100 protein beta chain; S-100 protein subunit beta; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium binding protein beta chain; S100 calcium-binding protein B; S100 protein beta chain; S100B_HUMAN; S100beta; S100 _; S100-_; S100_. |
| Background | S100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. |
| Application Dilution | |
| ELISA | 1:500-1000 |
Frequently asked questions
Which applications is Human S100B (7F3) Monoclonal Antibody, HRP Conjugated (bsm-41680M-HRP) validated for, and at what dilution?
bsm-41680M-HRP is validated for ELISA (1:500-1000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Human S100B (7F3) Monoclonal Antibody, HRP Conjugated (bsm-41680M-HRP) react with?
Tested reactivity: Human.
How should bsm-41680M-HRP be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Human S100B (7F3) Monoclonal Antibody, HRP Conjugated (bsm-41680M-HRP)?
Recombinant human S100B protein