Bcl-XL Recombinant Antibody, AbBy Fluor-350 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52024r-bf350-100uL |
| Product Name | Bcl-XL Recombinant Antibody, AbBy Fluor-350 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-350 |
| Host | Rabbit |
| Source | Recombinant human Bcl-XL protein, around 1-100aa. |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 598 |
| Swiss Prot | Q07817 |
| Synonyms | BCL2L1 phospho T47; BCL2L1 phospho Thr47; p-BCL2L1 phospho T47; p-BCL2L1 Thr47; p-BCL2L1Thr115; Apoptosis regulator Bcl X; BclX; Bcl-X; Bcl 2 like 1; Bcl 2 like 1 protein; Bcl xL; BCL X/L; BCL XL/S; Bcl xS; Bcl2 like1; BCL2-related gene; BCL2-related protein, long isoform, included; BCLXL, included; BCL2-related protein, short isoform, included; BCLXS, included; BCL2L; BCL2L1; Bclx; DKFZp781P2092; MGC113803; MGC99998; B2CL1_HUMAN. |
| Background | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is Bcl-XL Recombinant Antibody, AbBy Fluor-350 Conjugated (bsm-52024R-BF350) validated for, and at what dilution?
bsm-52024R-BF350 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Bcl-XL Recombinant Antibody, AbBy Fluor-350 Conjugated (bsm-52024R-BF350) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-52024R-BF350 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Bcl-XL Recombinant Antibody, AbBy Fluor-350 Conjugated (bsm-52024R-BF350)?
Recombinant human Bcl-XL protein, around 1-100aa.
What are the excitation and emission wavelengths of the AbBy Fluor-350 conjugate (bsm-52024R-BF350)?
AbBy Fluor-350 on bsm-52024R-BF350: excitation / emission 346nm/442nm.