VDAC1 Recombinant Antibody, Cy3 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-52251r-cy3-100uL |
| Product Name | VDAC1 Recombinant Antibody, Cy3 Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Cy3 |
| Host | Rabbit |
| Source | Human VDAC1 protein between 1 to 100 amino acids |
| Immunogen Range | 1-100/283 |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 7416 |
| Swiss Prot | P21796 |
| Synonyms | Voltage-dependent anion-selective channel protein 1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC-1, hVDAC1 |
| Background | Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | |
Frequently asked questions
Which applications is VDAC1 Recombinant Antibody, Cy3 Conjugated (bsm-52251R-Cy3) validated for, and at what dilution?
bsm-52251R-Cy3 is validated for WB (1:300-5000); IF. These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does VDAC1 Recombinant Antibody, Cy3 Conjugated (bsm-52251R-Cy3) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-52251R-Cy3 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise VDAC1 Recombinant Antibody, Cy3 Conjugated (bsm-52251R-Cy3)?
Human VDAC1 protein between 1 to 100 amino acids Immunogen range: 1-100/283.
What are the excitation and emission wavelengths of the Cy3 conjugate (bsm-52251R-Cy3)?
Cy3 on bsm-52251R-Cy3: excitation / emission 512,550nm/570,615nm.