| Overview |
| bsm-62560r-biotin-100ul |
| ABRAXAS1 Recombinant Antibody, Biotin Conjugated |
| WB, IP |
| Human |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human ABRAXAS1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 84142 |
| Q6UWZ7 |
| Nucleus |
| ABRA1; ABRAXAS; FAM175A. |
| Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. |
| Application Dilution |
| WB |
1:300-5000 |
| IP |
1-2ug |
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