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FANCD2 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated

Applications

  • WB
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-61302r-apc-cy5-100uL
Product Name FANCD2 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated
Applications
WB IF(ICC)
Reactivity Human, Mouse, Rat
Specifications
Conjugation APC-Cy5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human FANCD2
Clonality Monoclonal
Clone # Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2177
Swiss Prot Q9BXW9
Subcellular location Nucleus
Synonyms FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANCD 2; FANCD; FANCD2; Fanconi anemia group D2 protein; FLJ23826; Protein FACD2; Type 4 Fanconi pancytopenia.
Background Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200

Frequently asked questions

Which applications is FANCD2 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated (bsm-61302R-APC-Cy5) validated for, and at what dilution?

bsm-61302R-APC-Cy5 is validated for WB (1:300-5000); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does FANCD2 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated (bsm-61302R-APC-Cy5) react with?

Tested reactivity: Human, Mouse, Rat.

How should bsm-61302R-APC-Cy5 be stored?

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise FANCD2 Recombinant Monoclonal Antibody, APC-Cy5 Conjugated (bsm-61302R-APC-Cy5)?

KLH conjugated synthetic peptide derived from human FANCD2

What are the excitation and emission wavelengths of the APC-Cy5 conjugate (bsm-61302R-APC-Cy5)?

APC-Cy5 on bsm-61302R-APC-Cy5: excitation / emission 650nm/670nm.

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US only. One sample per paid order, subject to review. Backorders may ship separately. Confirm Free at checkout. Check application and species suitability; same target does not guarantee equivalent performance. For research use only.

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