CDYL Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-53086R |
| Product Name | CDYL Polyclonal Antibody |
| Applications |
ELISA
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Polyclonal antibody raised in rabbit against human CDYL (chromodomain protein, Y-like) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein |
| Clonality | Polyclonal |
| Isotype | Not Determined |
| Concentration | Not Determined |
| Purification | Whole antiserum from rabbit containing 0.05% azide |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 9425 |
| Swiss Prot | Q9Y232 |
| Synonyms | CDYL1, Chromodomain Y-like protein, CDYL |
| Background | Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4. |
| Application Dilution | |
| ELISA | 1:500-1000 |