human CD10/PE
Applications
Reactivity
Overview | |
Catalog # | bsm-30012M-PE |
Product Name | human CD10/PE |
Applications | FCM |
Reactivity | Human |
Specifications | |
Conjugation | Unconjugated |
Host | Mouse |
Clonality | Monoclonal |
Clone # | 10F8 |
Isotype | IgG2b/Kappa |
Concentration | n/a |
Purification | Affinity purified by Protein G |
Storage Buffer | 0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
Storage Condition | Store at 2-8℃. Protect from light. Avoid freezing. |
Target | |
Gene ID | 4311 |
Swiss Prot | P08473 |
Synonyms | NEP_HUMAN; Neprilysin; MME; membrane metalloendopeptidase; NEP; SFE; CD10; CALLA; CMT2T; SCA43; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; Neutral endopeptidase; Skin fibroblast elastase; |
Background | The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017] |
Application Dilution | |
FCM | 1:20-100 |