human CD279 (PD-1)/FITC

Overview
Catalog #	bsm-30140m-fitc-100t
Product Name	human CD279 (PD-1)/FITC
Applications	FCM
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Clonality	Monoclonal
Clone #	3A9
Isotype	IgG1/Kappa
Concentration	n/a
Purification	Affinity purified by Protein G
Storage Buffer	0.01M PBS, 0.5%BSA, 0.02% Proclin300
Storage Condition	Store at 2-8°C
Target
Gene ID	5133.0
Swiss Prot	Q15116
Synonyms	Programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2.
Background	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Application Dilution
FCM	10ul/10^6 cells in 100ul