Dymeclin Polyclonal Antibody

$Formalin-fixed and paraffin embedded rat brain labeled with Anti-Dymeclin Polyclonal Antibody, Unconjugated (bs-13037R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.\\n$

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Dymeclin Polyclonal Antibody, Unconjugated (bs-13037R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.\\n

$Formalin-fixed and paraffin embedded human kidney labeled with Anti-Dymeclin Polyclonal Antibody, Unconjugated (bs-13037R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.\\n$

Formalin-fixed and paraffin embedded human kidney labeled with Anti-Dymeclin Polyclonal Antibody, Unconjugated (bs-13037R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.\\n

Applications

WB
ELISA
IHC-P
IHC-F
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Human
Rat

Predicted Reactivity

Mouse
Dog
Cow
Sheep
Horse

Overview
Catalog #	bs-13037R
Product Name	Dymeclin Polyclonal Antibody
Applications	WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Human, Rat
Predicted Reactivity	Mouse, Dog, Cow, Sheep, Horse
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human Dymeclin
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	54808
Subcellular location	Cytoplasm
Synonyms	DMC; Dyggve-Melchior-Clausen syndrome protein; DYM; FLJ20071; FLJ90130; SMC; DYM_HUMAN.
Background	Dyggve-Melchior-Clausen syndrome (DMC), a rare autosomal recessive disorder, is characterized by microcephaly, short trunk dwarfism and sometime psychomotor retardation. Cutaneous cells of affected individuals show dilated rough endoplasmic reticulum and enlarged vacuoles. The Dyggve-Melchior-Clausen syndrome protein, also designated dymeclin, may play a role in proteoglycan metabolism and intracellular protein digestion. It is a widely expressed multi-pass membrane protein, detected primarily in chondrocytes and fetal brain tissue. Defects in dymeclin are also the cause of Smith-McCort dysplasis syndrome (SMC), which has characteristics identical to those of Dyggve-Melchior-Clausen syndrome.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200