Hydroxyfasudil HCl

Overview
Catalog #	bs-6872c-10mg
Product Name	Hydroxyfasudil HCl
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 343.83 Formula: C14 H18 Cl N3 O3 S CAS Number: 155558-32-0 InChi Key: XWWFOUVDVJGNNG-UHFFFAOYSA-N InChi: InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H Smiles: Cl.OC1N=CC=C2C(=CC=CC2=1)S(=O)(=O)N1CCCNCC1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	Hydroxyfasudil, aslo known as HA1100, is a cell-permeable hydroxylated metabolite of HA-1077, is a potent inhibitor of Rho-associated kinase (ROCK) (Ki = 150 nM). Hydroxyfasudil alleviates demyelination through the inhibition of MOG antibody and microglia activation in cuprizone mouse model.