AZD9496

Overview
Catalog #	bs-7101c-10mg
Product Name	AZD9496
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 442.47 Formula: C25 H25 F3 N2 O2 CAS Number: 1639042-08-2 InChi Key: DFBDRVGWBHBJNR-BBNFHIFMSA-N InChi: InChI=1S/C25H25F3N2O2/c1-14-10-17-16-6-4-5-7-20(16)29-23(17)24(30(14)13-25(2,3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9,11-12,14,24,29H,10,13H2,1-3H3,(H,31,32)/b9-8+/t14-,24-/m1/s1 Smiles: C[C@@H]1CC2=C(NC3=CC=CC=C32)[C@@H](C2C(F)=CC(=CC=2F)/C=C/C(O)=O)N1CC(C)(C)F Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years
Description	AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. AZD9496 is curently under clinical trials. AZD9496 may be useful for the treatment of ER+ breast cancer.