RAMB4

Overview
Catalog #	bs-7117c-10mg
Product Name	RAMB4
Specifications
Storage Buffer	Powder
Storage Condition	Store in dry, dark place at -20C for 1 year.
Target
Product Information	Molecular Weight: 413.12 Formula: C19 H13 Cl4 N O CAS Number: 145888-79-5 InChi Key: GJPXGFGIFQWUOC-ACFHMISVSA-N InChi: InChI=1S/C19H13Cl4NO/c20-15-3-1-11(7-17(15)22)5-13-9-24-10-14(19(13)25)6-12-2-4-16(21)18(23)8-12/h1-8,24H,9-10H2/b13-5+,14-6+ Smiles: O=C1/C(/CNC/C/1=C\C1=CC(Cl)=C(Cl)C=C1)=C/C1=CC(Cl)=C(Cl)C=C1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power. Shelf Life: 1.0 years
Description	RAMB4, also known as PTP1B-IN-9, is a ubiquitin-proteasome system (UPS)-stressor. RAMB4 selectively reduces the viability of cervical cancer cells independently of HPV genotype via blockade of proteasomal degradation. RAMB4 treatment triggers a Ubiquitin-Proteasome-System (UPS)-stress response without affecting 20S proteasome catalytic activities.