Luteolin

Overview
Catalog #	bs-75081c-5mg
Product Name	Luteolin
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 491-70-3 Molecular formula: C15H10O6 Molecular weight: 286.2 Purity: >98% (HPLC) Appearance: Yellow solid. Solubility: Soluble in DMSO, DMF, methanol or ethanol. Slightly soluble in water. InChiKey: IQPNAANSBPBGFQ-UHFFFAOYSA-N SMILES: OC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=C(O)C(O)=C1
Description	Anticancer and antimetastatic agent that induces apoptosis and modulates autophagy. Shown to inhibits kinase signalling, including PKC(epsilon) and Src kinase, HDAC, Phosphatidylinositol 3-kinase (PI3K) / Akt and p90 ribosomal S6 kinase (RSK1/RSK2). Topoisomerase I Inhibitor. Anti-inflammatory agent that inhibits 15-Lipoxygenase (15-LOX) and IL-6 production. Antioxidant. Free radical scavenger. Antiadipogenic agent, that inhibits PPAR-gamma, fatty acid synthase (FAS) and alpha-Glucosidase. Neuroprotective. Monoamine transporter activator and inhibitor of phosphodiesterases 1-5 (PDE1-5). Shown to selectively inhibits chymotrypsin-like and trypsin-like proteasome catalytic activity.