Rasfonin

Overview
Catalog #	bs-75153c-500ug
Product Name	Rasfonin
Specifications
Storage Buffer	Liquid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 303156-68-5 Molecular formula: C25H38O6 Molecular weight: 434.6 Purity: >95% (HPLC) Appearance: Tan to brown viscous liquid (oily). Solubility: Soluble in ethanol, methanol or DMSO (all 1mg/ml). InChiKey: OHRGHFXATDKGOV-MDKHPKFKSA-N SMILES: O=C1O[C@@]([C@H](C[C@@H](C)C/C(C)=C/C)C)([H])C(OC(/C=C/C(C)=C/[C@@H](CO)CCO)=O)C=C1
Description	Selective apoptosis inducer in ras-dependent cells. Autophagy (Akt-dependent), apoptosis and necroptosis inducer in renal cancer cell lines. Induces death of ras-mutated pancreatic tumor (Panc-1) cells in vitro and in vivo. Robust inhibitor of pancreatic cancers with the K-ras mutation. Reduced Sos1 expression and depressed Ras-MAPK activity.