Sipholenol A

Overview
Catalog #	bs-75261c-100ug
Product Name	Sipholenol A
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 78518-73-7 Molecular formula: C30H52O4 Molecular weight: 476.7 Purity: >98% (HPLC) Appearance: White to off-white lyophilized powder. Solubility: Soluble in DMSO or 100% ethanol (25mg/ml). InChiKey: LVWWPNAIMBYRKG-KOHQYJKCSA-N SMILES: CC(O1)(C)[C@H](O)CC[C@@]2(C)[C@@]1([H])CC[C@@](O)(C)[C@@H]2CC[C@@H]3C(C)(C)[C@@](CC[C@@]4(C)O)([H])[C@@]4([H])CC=C3C
Description	Efficient inhibitor of P-glycoprotein (Pgp, MDR-1) function through direct interactions. By inhibiting MDR-1, active compounds remain in the cytoplasm longer and allowing them to be more effective within the cell. Reversing agent for the treatment of multidrug resistance (MDR) in Pgp-overexpressing tumors. Potentiates the cytotoxicity of established Pgp substrates such as colchicine, vinblastine and paclitaxel. Antiproliferative and cytotoxic compound. Potent antifouling compound.