Daptomycin

Overview
Catalog #	bs-75285c-25mg
Product Name	Daptomycin
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 103060-53-3 Molecular formula: C72H101N17O26 Molecular weight: 1620.7 Purity: >95% (HPLC) Appearance: Off-white to pale yellow powder. Solubility: Soluble in water (25mg/ml), DMSO (50mg/ml) or methanol (5mg/ml). InChiKey: DOAKLVKFURWEDJ-RWDRXURGSA-N SMILES: O=C(O[C@H](C)[C@H](NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](NC(CCCCCCCCC)=O)CC1=CNC2=C1C=CC=C2)=O)CC(N)=O)=O)=O)C(NC3)=O)[C@H](CC(C4=C(N)C=CC=C4)=O)NC([C@@H](NC([C@@H](CO)NC(CNC([C@H](CC(O)=O)NC([C@@H](C)NC([C@H](CC(O)=O)NC([C@@H](NC3=O)CCCN)=O)=O)=O)=O)=O)=O)[C@H](C)CC(O)=O)=O
Description	Daptomycin, a naturally occurring cyclic lipopeptide, is a calcium-dependent antibiotic. It exhibits potent bacteriocidal activity against most Gram-positive bacteria in vitro and in vivo, including antibiotic-resistant strains such as MRSA and VRE. Daptomycin disrupts the bacterial plasma membrane function, which results in membrane depolarization consequently leading to inhibition of protein, DNA and RNA synthesis, essential for cell division and cell wall synthesis.