Q-VD-OPh
| Overview | |
| Catalog # | bs-75292c-1mg |
| Product Name | Q-VD-OPh |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 3 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 1135695-98-5 (anhydrous) Molecular formula: C26H25F2N3O6 Molecular weight: 513.5 Purity: >95% (TLC) Appearance: White solid. Solubility: Soluble in DMSO. InChiKey: OOBJCYKITXPCNS-AKRCKQFNSA-N SMILES: CC(C)[C@H](NC(=O)C1=CC=C2C=CC=CC2=N1)C(=O)NC(CC(O)=O)C(=O)COC1=C(F)C=CC=C1F |
| Description | Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Used in apoptosis and inflammasome studies. |
Powered by Bioz