BLZ-945

Overview
Catalog #	bs-75511c-1mg
Product Name	BLZ-945
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 953769-46-5 Molecular formula: C20H22N4O3S Molecular weight: 398.5 Purity: >95% Appearance: Pale yellow solid. Solubility: Soluble in DMSO. Slightly soluble in ethanol. Insoluble in water. InChiKey: ADZBMFGQQWPHMJ-RHSMWYFYSA-N SMILES: CNC(=O)C1=CC(OC2=CC=C3N=C(N[C@@H]4CCCC[C@H]4O)SC3=C2)=CC=N1
Description	Anticancer compound. Orally active, potent and selective colony stimulating factor 1 receptor (CSF-1R; c-Fms) inhibitor. More than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and platelet-derived growth factor receptor beta (PDGFRbeta). Selective against more than 200 additional kinases [2].