Actinomycin D
| Overview | |
| Catalog # | bs-75679c-5mg |
| Product Name | Actinomycin D |
| Specifications | |
| Storage Buffer | Crystals |
| Storage Condition | Stable for 1 year after receipt when stored at +4°C. After reconstitution protect from light at -20°C. |
| Target | |
| Product Information | CAS Number: 50-76-0 Molecular formula: C62H86N12O16 Molecular weight: 1255.4 Purity: >98% (HPLC) Appearance: Red shiny crystals. Solubility: Soluble in DMSO, 100% ethanol or methanol. InChiKey: ZOWMRHVAQGTFTG-IZRKADTCSA-N SMILES: CC(C)[C@@H]1NC(=O)[C@H](NC(=O)C2=CC=C(C)C3=C2N=C2C(O3)=C(C)C(=O)C=C2C(=O)N[C@@H]2[C@H](C)OC(=O)[C@@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@H]3CCCN3C(=O)[C@@H](NC2=O)C(C)C)[C@H](C)OC(=O)[C@@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@H]2CCCN2C1=O |
| Description | Antibiotic. Antitumor compound [2]. Cytotoxic [2]. Apoptosis inducer [1, 2, 6, 7]. RNA synthesis inhibitor [4]. DNA intercalating agent [3, 5]. Mcl-1 expression inhibitor [8] p53 pathway activator [9]. |