Sulfo-NHS-LC-Biotin sodium salt

Overview
Catalog #	bs-75968c-10mg
Product Name	Sulfo-NHS-LC-Biotin sodium salt
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 191671-46-2 or 127062-22-0 Molecular formula: C20H29N4NaO9S2 Molecular weight: 556.59 Purity: >90% (NMR) Appearance: White to off-white powder. Solubility: Soluble in water (10mg/ml), DMSO or DMF. InChiKey: JJGWLCLUQNFDIS-GTSONSFRSA-M SMILES: O=C(NCCCCCC(ON1C(CC(S(=O)([O-])=O)C1=O)=O)=O)CCCC[C@@H]2SC[C@@]3([H])[C@]2([H])NC(N3)=O.[Na+]
Description	Sulfo-NHS-LC-Biotin is an amino-reactive biotinylation reagent with a long spacer arm. The 6-aminocaproic acid spacer arm provides distance between the biotin and the target ligand which helps alleviate steric hindrance, in addition it forms permanent amide bonds. The sodium sulfonate groups render this compound water-soluble and prevent it from crossing the lipid bi-layer of the cell membrane, making it a tool to label cell surface proteins. In addition, Sulfo-NHS-LC-Biotin is used to biotinylate antibodies, proteins, peptides, or amino acids by reacting with primary amines as found in the N-terminus and Lysine side chains. Optimal reaction conditions are at a pH of 7-9. Avoid amine-containing buffers, which may compete in the acylation reaction.