Corilagin

Overview
Catalog #	bs-76083c-10mg
Product Name	Corilagin
Specifications
Storage Buffer	Powder
Storage Condition	Stable for 2 years after receipt when stored at +4°C.
Target
Product Information	CAS Number: 23094-69-1 Molecular formula: C27H22O18 Molecular weight: 634.45 Purity: >98% (HPLC) Appearance: White to off-white powder. Solubility: Soluble in DMSO, DMF or ethanol (all 20mg/ml). Slightly soluble in water (1mg/ml). InChiKey: TUSDEZXZIZRFGC-XIGLUPEJSA-N SMILES: O=C(O[C@H]([C@H]1O)[C@H](O)[C@H](O[C@H]1OC(C2=CC(O)=C(O)C(O)=C2)=O)COC3=O)C4=CC(O)=C(O)C(O)=C4C5=C3C=C(O)C(O)=C5O
Description	Corilagin is a polyphenol and hydrolyzable tannin that can be isolated from a variety of plants. It inhibits squalene epoxidase, a key enzyme in cholesterol synthesis and has various anti-inflammatory and anti-cancer effects. This compound displays the ability to inhibit NF-kappaB pathway activation and also prevent the release of TNF-alpha. Additional studies show that Corilagin significantly inhibits type 1 plasminogen activator inhibitor (PAI-1) in rat plasma. Shown to have antioxidant, antiviral and hepatoprotective properties. Induces apoptosis, autophagy and ROS generation in several cell lines.